Allipra-650 tablets are used for the relief of mild to moderate pain and to reduce fever associated with various conditions, making it effective for headaches, toothaches, and muscle aches. 

ALLIPRA-650:

Allipra 650 is used to relieve mild to moderate pain, such as headaches, muscle aches, toothaches, and menstrual cramps. It also reduces fever caused by colds, flu, or infections. It is commonly used for general pain relief and is considered safer for short-term use compared to NSAIDs, especially for those with gastrointestinal concerns.

composition:

Paracetamol IP 650mg

Uses

1. Pain Relief: Used to alleviate mild to moderate pain, including headaches, toothaches, muscle aches, and joint pain.

2. Fever Reduction: Effective in reducing fever associated with various conditions, such as infections and illnesses.

Dosage

• Typical Adult Dose:

  • The usual dose is 650 mg every 4 to 6 hours as needed, not exceeding 3000 mg (3 grams) per day to avoid toxicity.

• Administration: Tablets can be taken with or without food, but it’s best to follow the instructions provided on the label or by a healthcare provider.

Mechanism of Action

Paracetamol (650 mg), also known as acetaminophen, is a widely used analgesic (pain reliever) and antipyretic (fever reducer).The mechanism of action is complex and includes the effects of both the peripheral (COX inhibition), and central (COX, serotonergic descending neuronal pathway, L-arginine/NO pathway, cannabinoid system) antinociception processes and “redox” mechanism.

Side Effects

1. Gastrointestinal Issues: Nausea or upset stomach may occur in some individuals.

2. Allergic Reactions: Rarely, it can cause skin rashes or other allergic reactions.

3. Liver Damage: Overdose or prolonged use can lead to severe liver damage, which may be life-threatening.

Precautions

1. Allergies: Avoid use if allergic to paracetamol or any of its components.

2. Liver Disease: Use with caution in individuals with liver disease or alcohol dependence; dosage adjustments may be necessary.

3. Pregnancy and Breastfeeding: Generally considered safe, but consult a healthcare provider before use during pregnancy or breastfeeding.

4. Medication Interactions: Inform your healthcare provider about all medications you are taking, as some may interact with paracetamol.

**Always take paracetamol as directed by your healthcare provider, and report any unusual symptoms or side effects promptly.