ESTRALOG-DS TABLETS

“Estralog-DS Tablets are primarily used to manage chronic kidney disease (CKD) by improving protein metabolism and reducing uremic toxins, thereby slowing disease progression. They support diabetic nephropathy by aiding kidney function in diabetic patients and provide nutritional support for those on a low-protein diet, ensuring they receive essential nutrients. These tablets help maintain proper nutrition and overall kidney health in individuals with compromised kidney function“.

COMPOSITION:

(each tablet contain)
L-Theanine 53 mg
Calcium-2-oxo-3-phenylpropionate 68 mg
Calcium-3-methyl-2-oxo-butyrate 86 mg
Calcium-4-methyl-2-oxo-valerate 101 mg
L-Tyrosine 30 mg
Calcium-3-methyl-2-oxo-valerate 67 mg
L-Lysine Acetate 105 mg
Calcium DL-2-hydroxy-4(methylthio) butyrate 23 mg
L-Tryptophan 23 mg
L-Histidine 34 mg

Uses:

1. Kidney Disease Management: Helps in managing chronic kidney disease (CKD) by providing essential nutrients while reducing nitrogen load.

2. Nutritional Support: Provides essential amino acids for patients who have increased protein requirements or are on restricted protein diets.

3. Muscle Preservation: May aid in preserving muscle mass in patients with muscle wasting conditions.

Dosage:

• Typical Adult Dose: The dosage can vary widely based on individual needs, but a common recommendation is to take 1 to 3 tablets daily, as directed by a healthcare provider. It’s crucial to follow the dosage instructions provided on the product label or by a physician.

• Administration: Tablets should be taken with water, preferably on an empty stomach or as directed.

Mechanism of Action:

Alpha-ketoanalogues are nitrogen-free precursors of essential amino acids. In the body, they undergo a process called transamination, where they bind nitrogen from non-essential amino acids to form essential amino acids. This process reduces the production of urea, thereby lowering toxin levels in the blood. By minimizing nitrogen waste, these tablets support better protein metabolism, reduce strain on the kidneys, and slow the progression of chronic kidney disease, especially when used in conjunction with a low-protein diet.

Side Effects:

1. Gastrointestinal Issues: Nausea, vomiting, diarrhea, or abdominal discomfort.

2. Allergic Reactions: Rarely, some individuals may experience allergic reactions, including rash or itching.

3. Metabolic Imbalance: High doses could potentially lead to imbalances in amino acids or electrolytes.

Precautions:

1. Kidney Function: Use with caution in individuals with advanced kidney disease; consult a healthcare provider before use.

2. Allergies: Avoid if allergic to any of the components in the formulation.

3. Medication Interactions: Discuss any current medications with a healthcare provider, as there may be interactions, particularly with those affecting kidney function.

4. Pregnancy and Breastfeeding: Consult a healthcare provider before use during pregnancy or breastfeeding.

**Always follow the advice of a healthcare professional regarding the use of alpha-ketoanalogues and essential amino acids and report any side effects or unusual symptoms promptly.