ESTRASAFE TABLETS

Estrasafe is a combination of Acetylcysteine and Taurine  has antioxidant properties which helps in elimination of toxic materials such as urea from the kidneys and improves kidney function. Acts as a mucolytic agent, reducing sputum viscosity and helping manage conditions like chronic bronchitis, COPD, and cystic fibrosis. Also used to treat acetaminophen (paracetamol) overdose by replenishing glutathione levels, which helps prevent liver damage.

Composition:

Acetylcysteine 150mg and Taurine 500mg 

Uses:

• Diabetic Kidney Disease: Helps manage and treat diabetic nephropathy by supporting kidney function and preventing the progression of kidney damage.

• Chronic Kidney Disease: Assists in managing chronic kidney diseases by reducing oxidative stress and inflammation in the kidneys.

• Respiratory Disorders: Acts as a mucolytic agent, reducing sputum viscosity and helping manage conditions like chronic bronchitis, COPD, and cystic fibrosis.

• Acetaminophen Toxicity: Used to treat acetaminophen (paracetamol) overdose by replenishing glutathione levels, which helps prevent liver damage

Dosage:

• Typical Adult Dose:

  • 1 tablet, 1-2 times daily with food, or as prescribed by a doctor, for general support of respiratory health and liver protection.

• For Respiratory Conditions: The dosage may vary depending on severity and response to treatment.

• For Liver Protection (in case of overdose), the dosage should follow the medical guidelines based on the severity and timing of the overdose.

• Administration: Tablets should be taken as directed by a healthcare provider, and it’s advisable to drink plenty of fluids while taking acetylcysteine.

Mechanism of Action:

• N-Acetylcysteine + Taurine is an antioxidant and mucolytic combination.

• N-Acetylcysteine is a precursor to glutathione, the body’s main cellular antioxidant. It works by neutralising harmful substances within the liver and breaking down mucus to make it less sticky and easier to cough up.

• Taurine is a type of amino acid that plays an important role in various bodily functions. It maintains the balance of water and mineral salts in your blood, stabilises cell membranes, and helps control calcium levels within cells. It also enhances insulin action and exhibits neuroprotective properties by modulating certain brain receptors.

Side Effects:

• Gastrointestinal issues: nausea, vomiting, diarrhea, or abdominal pain.

• Allergic reactions: skin rash, itching, or difficulty breathing (rare).

• Headache or dizziness.

• Generally well-tolerated, but some individuals may experience mild gastrointestinal disturbances or allergic reactions.

Precautions:

• Allergies: Avoid use if allergic to acetylcysteine, taurine, or any components of the formulation.

• Asthma: Use with caution in patients with asthma, as it may trigger bronchospasm in some individuals.

• Liver and Kidney Disease: Consult a healthcare provider before use in patients with liver or kidney impairment.

• Pregnancy and Breastfeeding: Consult a healthcare provider before use during pregnancy or breastfeeding.

• Medication Interactions: Inform your healthcare provider about all medications being taken, as there may be potential interactions.

**Always follow your healthcare provider’s instructions regarding the use of Acetylcysteine and Taurine and report any unusual symptoms or side effects promptly.