MESTRACOB-PLUS injection is used to treat vitamin B deficiencies, support nerve health, and help manage conditions like neuropathy, fatigue, and anemia resulting from low levels of vitamins B12, B3, and B6. 

MESTRACOB-PLUS INJECTION

“It is used to treat and prevent vitamin and nutritional deficiencies. This medication also addresses vitamin B6 deficiency, anemia, peripheral neuropathy (nerve damage),and  seizures. Additionally, it supports overall neurological health and can be beneficial in treating certain hereditary disorders such as hyperoxaluria and homocystinuria“.

composition

METHYLCOBALAMIN 1500mg, NICOTINAMIDE 100mg & PYRIDOXINE HCL 100mg

Uses

This injection may be used to address conditions related to vitamin deficiency, including:

1. Neuropathy – Often used for treating nerve-related pain, numbness, or tingling, particularly in diabetic patients or those with peripheral neuropathy.

2. Vitamin B Deficiency – Used to address deficiencies that can lead to fatigue, anemia, and neurological issues.

3. Support for Energy Metabolism – Helps improve energy metabolism and supports overall nerve function and red blood cell formation.

Dosage

The dosage is typically determined by a healthcare provider based on the patient’s medical condition, vitamin levels, and response to treatment. Generally, the injection is administered once every few days to once a week, depending on the severity of deficiency or condition being treated.

• Adult Dosage: Generally, 1 ampoule (containing 1500 mcg Methylcobalamin, 100 mg Nicotinamide, and 100 mg Pyridoxine HCl) may be administered intramuscularly or intravenously once as prescribed by a healthcare provider.

Mechanism of Action

• Methylcobalamin (1500 mg): A form of Vitamin B12 that acts as a coenzyme, aiding in DNA synthesis, energy production, and maintaining normal homocysteine levels.

• Nicotinamide (100 mg): Also known as Vitamin B3, it supports cellular energy metabolism, DNA repair, and regulation of transcription processes as part of the coenzyme NAD.

• Pyridoxine HCl (100 mg): Also known as Vitamin B6, it is involved in amino acid and neurotransmitter metabolism, homocysteine breakdown, and hemoglobin synthesis

Side Effects

While this injection is usually well-tolerated, some patients may experience mild to moderate side effects, including:

• Common Side Effects:

  • Pain or discomfort at the injection site

  • Mild itching or rash

  • Headache or dizziness

  • Nausea or gastrointestinal discomfort

• Serious Side Effects (Rare):

  • Severe allergic reactions such as swelling, itching, or rash

  • Breathing difficulties

  • Fast or irregular heartbeat

  • Tingling or numbness not associated with the underlying condition

If any severe or unusual symptoms occur, seek medical attention immediately.

Precautions

1. Allergy Check: Before starting treatment, inform your healthcare provider if you have any known allergies, especially to any form of Vitamin B, including Methylcobalamin, Nicotinamide, or Pyridoxine.

2. Existing Conditions: Patients with certain medical conditions (e.g., kidney disease, liver disease, diabetes) should use this injection with caution and under medical supervision.

3. Pregnancy and Breastfeeding: Consult a healthcare provider before using this injection if you are pregnant or breastfeeding to understand potential risks.

4. Interactions: This injection may interact with certain medications (e.g., antiepileptic drugs, other vitamin supplements). Inform your doctor of all medications and supplements you are currently taking.

5. Overdose Risk: Avoid self-administering or exceeding the recommended dose as high levels of vitamins, especially B6, may lead to toxicity over time.

**Always follow your healthcare provider’s instructions and report any unusual symptoms immediately.